【Cell Factory-04】

This course of the Academy of Biological Sciences is to let them participate in the process of human birth as cells. Before, everyone had no clear concept in their hearts, and their brains were all confused. It was not until this moment, when they heard the "thumping" sound of the baby's heart beating, that they finally felt the sacred sense of "creating new life".

Especially, this baby's heart was made by Xu Yishen himself!

The rhythm of the heartbeat encouraged everyone. Yue Xingwen rolled his eyes, looked at Jiang Pingce next to him, and said with a smile, "Our baby has a heartbeat!"

Jiang Pingce: "...Well."

Everyone: "????"

Why is it weird to hear the two of you talking?

Ke Shaobin suddenly said: "Do you think that the baby's heartbeat is so fast? It's more than 100 times in this minute, right?"

Liu Zhaoqing explained: "A normal adult's heart rate is 60 to 70 beats a minute, but a baby's heart rate will be very high, and it is normal to exceed 100. The heart beats fast to supply blood to the whole body of the baby and make the cells grow rapidly."

Ke Shaobin suddenly realized: "Oh, that's good, I'm also worried that the baby will have congenital heart disease."

Xu Yishen's voice came from where his heart was beating: "Don't worry, I will close the internal structure of the heart."

As soon as the voice fell, a mechanical voice sounded again in everyone's ears: "At 6 weeks of pregnancy, the heart beats regularly, begins to divide the ventricles, and supplies blood to the whole body of the fetus. The cells of the fetus divide rapidly, the embryonic kidney develops, and the neural tube begins to connect to the brain. and the spinal cord begins to develop."

As the prompt tone fell, a large number of pathways appeared in the "fetus" model space where everyone was located.

Xu Yishen asked: "The heart of a fetus is only divided into the left atrium and the right ventricle at the beginning, and later it will gradually be divided into the left and right atrium and the left and right ventricles. Brother Liu, am I right?"

Liu Zhaoqing said: "Yes, it is divided into the atrium and the ventricle first, and the atrioventricular valve is formed between them to ensure that the blood can only flow in one direction and not backflow; in the later stage, the atrium forms the atrial septum, which is divided into left and right; the ventricle forms the interventricular septum. , divided into left and right, the whole heart is not fully developed. Note that the valve between the atrium and the ventricle, the arch faces the atrium."

Xu Yishen said: "That is, to ensure that blood can only flow from the atrium to the ventricle?"

Liu Zhaoqing said, "Yes."

The special valve between the atrium and the ventricle is called the atrioventricular valve. This is like a switch, which only opens towards the ventricle, which ensures that blood can only flow from the atrium to the ventricle. When the flow is reversed, it will be blocked by the valve.

Xu Yishen quickly found the valve area, and quickly prepared the atrioventricular valve of the heart according to the regional prompts.

The next moment, I listened to the mechanical voice: "Please establish a whole-body blood circulation network, dredge the blood vessels in the whole body, and allow the fetus to form an independent blood circulation."

The circulatory system is also Xu Yishen's responsibility. Hearing this, he couldn't help but say with a headache: "The blood vessels in the whole body? I can't remember how many there are."

Liu Zhaoqing suggested: "Build the large blood vessels first, and then slowly build those capillaries later."

Yue Xingwen saw the spherical senior brother Xu Yishen rushing out of his heart and began to repair blood vessels all over his body like a worker repairing a road.

While repairing, Brother Xu said, "I remember, the blood circulation system is divided into pulmonary circulation and systemic circulation? I first make the pulmonary circulation. The blood comes out of the right ventricle and flows to the pulmonary artery. And then to the pulmonary veins, and finally back to the left atrium?"

Liu Zhaoqing praised: "Yes, the complete pulmonary circulation is such that the right ventricle exits and the left atrium returns. You first repair the pulmonary artery and pulmonary vein, and the capillary network can be slowly removed. The fetal lung tissue has not yet developed."

Xu Yishen let out a "hmm" and started working hard to repair the blood vessels.

Not far away, seeing Senior Brother Xu busy, Zhang Xiaonian couldn't help but said softly, "Making a child is really a huge project. We are about to become a human body construction team."

Ke Shaobin said seriously: "This child is the result of the efforts of 12 of us. Our child will be beautiful, smart and healthy."

Xin Yan said lightly: "And it's very edible."

Ke Shaobin: "..."

Xu Yishen quickly established the pulmonary circulation pathway, followed by the establishment of the "systemic circulation" pathway.

Liu Zhaoqing reminded next to him: "The systemic circulation, from the left ventricle, goes through the aorta to the blood vessels of the whole body, and then returns to the right atrium from the superior vena cava and inferior vena cava. The three major blood vessels are repaired first, and the latter is used for later use. The fetus must establish a complete The blood circulation system, after the separation of the ventricle and atrium."

Xu Yishen was busy for a while, and finally dredged all the major blood vessels. He smiled and said, "It's really tiring to make a baby! The blood vessels are done. I'll go back to my heart to split blood cells and prepare to transport blood."

Liu Zhaoqing said, "What about the kidneys? Who is responsible for the urinary system?"

Everyone looked at each other in dismay - it seems that no one was assigned to be responsible for the kidney just now, right?

Ke Shaobin whispered: "Everyone, hurry up, the baby can't be without kidneys!"

Everyone: "..."

Xu Yishen said: "The urinary system belongs to the mesoderm. Xingwen, Pingce, who are you two?"

Jiang Pingce said calmly, "I'll come."

The embryonic form of the two kidneys is formed in the sixth week of fetal development. With the kidneys, the fetus can slowly establish its own urinary system.

Although Jiang Pingce did not study medicine, he probably knew the location of the kidneys. After rolling over, he saw two pea-shaped signs. Corresponding organ graphics and annotated with soft blue highlights.

This will prevent everyone from creating a monster baby with "a liver growing out of the heart".

Jiang Pingce quickly began to divide, allowing cells to fill the area of ​​the two kidneys.

At the same time, due to Xu Yishen's efforts to make hemorrhagic cells, the blood circulation of the fetus was officially established. Everyone saw that the red light was flowing slowly along the blood vessels that Xu Yishen dredged. With each heartbeat, the fetus began to supply blood to the whole body!

A mechanical voice sounded again in the ear: "At 7 weeks of pregnancy, facial organs begin to develop, the outline of the eyes appears, the nostrils are wide open, and the ears are sunken. The buds of the hands, feet and limbs form, and muscle fibers and pituitary glands begin to develop."

Hearing this, everyone started to get busy.

Lan Yarong is in charge of the skin of the fetus, Xu Yishen reminded: "Senior Sister Lan, the skin needs to cover the whole body of the fetus, you have to follow the outline of the body from the beginning."

Lan Yarong said, "Understood."

However, the structure of the skin is relatively complex, divided into epidermis, dermis and subcutaneous tissue. There are many kinds of cells in the epidermis alone, Liu Zhaoqing said: "The ectoderm is responsible for the epidermis, which is divided into basal layer, spinous layer, and granule from the inside out. Layer, transparent layer and stratum corneum, Senior Sister Lan will have to work hard, you will be divided into five layers of cells."

Lan Yarong: "..."

Sure enough, she saw five passages on the periphery, and each floor had to surround the baby in a full circle.

She really worked hard for the baby's skin!

It's just that she doesn't know what the characteristics of cells in different layers are, so she can only ask for advice humbly: "I start building the skin barrier from the innermost layer, and the innermost layer is the basal layer, right? What do the cells look like?"

Liu Zhaoqing said: "Looks like columns, columnar epithelial cells."

So, Lan Yarong chose when the basal layer split.

The columnar cells, the plump Senior Sister Lan, suddenly turned into a tall pillar.

Seeing this scene, Liu Zhaoqing held back a smile and said, "Congratulations, you have changed from a spherical shape to a cylindrical shape."

Lan Yarong: "..."

She finally finished all the base layers, and there are four more layers to come!

Lan Yarong asked helplessly, "What about the fourth floor?"

Liu Zhaoqing said: "There are many protruding spinous cells."

Lan Yarong: "What about the particle layer?"

Liu Zhaoqing: "This layer, you have to become a spindle-shaped cell."

Lan Yarong's voice was weak: "The second layer, the transparent layer, right?"

Liu Zhaoqing: "This layer is flat cells."

Senior Sister Lan was like a ball that had been released from the air, and instantly flattened, turning into a flat and flat Senior Sister Lan. Liu Zhaoqing wanted to laugh a little when she saw it. It was really embarrassing for her. She changed and changed many styles.

On the last floor, Lan Yarong was so tired that she was almost out of breath. When she spoke, her voice sounded like she was dying: "Finally, there is one layer...the cuticle, what else will it change?"

Xu Yi squinted his eyes with a deep smile: "You girls often talk about exfoliating when you're skin care, and it's this layer that you go to."

Liu Zhaoqing smiled and said, "This layer is also flat cells, so hard!"

The flattened Senior Sister Lan finally finished repairing the outermost layer of the barrier, and said with emotion: "I usually only feel that the skin is very thin, but I didn't expect that human skin has so many layers of structure."

Liu Zhaoqing said, "This is the epidermis, and there is also the dermis under the epidermis."

Xu Yi said deeply: "By the way, the dermis is differentiated from the mesoderm. My blood circulation system is too busy. Who of you is responsible?"

Yue Xingwen took the initiative to say, "Come on, senior brother, tell me what I should do?"

Liu Zhaoqing said: "The dermis has many collagen fibers, reticular fibers, elastic fibers, and matrix. This layer is more complicated. Capillaries and nerves are distributed in the dermis, as well as some sweat glands, sebaceous glands, and hair follicles. With the cooperation of several people, Xingwen, you first build the approximate dermal barrier, and we have to fill in the vacant part."

Yue Xingwen said: "Okay."

He rolled over from Jiang Pingce's side, came behind the epidermal barrier built by Lan Yarong, and started to build the dermis layer. The dermis layer is distributed with a large number of fibrous structures to maintain the elasticity of the skin, and at the same time when the body is damaged fibrous tissue can also be responsible for the repair of the body's barrier.

Many of the fibrous structures are formed by the differentiation of cells called "fibroblasts".

Liu Zhaoqing said: "Xingwen, there are a lot of fibroblasts in the dermis, so you have to change the shape."

Yue Xingwen said: "I see. When I split, several options popped up in front of me. I first select fibroblasts and let these cells spread throughout the dermis of the whole body, right?"

Liu Zhaoqing: "That's right."

After the selection of Yue Xing's text, it was instantly deformed.

As you can see, the originally round and spherical Yuexingwen suddenly turned into a flat, somewhat irregular star-shaped cell. Since the cells are like being squashed, there is no place in front of them, so the eyes can only grow in "Top of the Head".

Jiang Pingce looked down and found that Xingwen was lying flat on the ground, his eyes blinking at the top of his forehead, a little confused.

Lan Yarong couldn't help laughing: "Alas, Xingwen's flat star shape is more cute."

Lin Manluo also smiled and said, "Xingwen is stunned, what should I do? After being flattened, I can't continue to roll forward!"

Qin Miao said, "Can you try to crawl forward?"

Lan Yarong said: "I have experience. After I became flat just now, I moved directly in the designated direction."

Yue Xingwen had no choice but to move to the side.

Everyone saw that a flat star-shaped cell quickly moved to the side in front of everyone's eyes. The two big eyes above the star were very innocent and dazed.

At this time, Yue Xingwen only had one idea: to create a child, it's so tiring! w, please keep in mind:,